Treatment of Primary Ovarian Failure with Genitourinary Symptoms of the Menopause

Clinical Scenario

Women with primary ovarian failure frequently experience genitourinary symptoms of the menopause (GSM) — changes affecting the vaginal, vulvar, and lower urinary tract — that are often not raised spontaneously. Proactive clinical enquiry is essential, as these symptoms are both common in this population and highly treatable.

Why This Presentation Requires Specific Attention

Genitourinary symptoms of the menopause in the setting of primary ovarian failure are under-recognised and under-reported. Because patients may not volunteer these concerns, clinicians should actively screen at each consultation. Identifying GSM allows timely, targeted intervention and meaningfully improves quality of life.

Treatment Approach (Partial Overview)

Management is centred on topical treatments directed at local vaginal and urinary tract symptoms. A range of topical options is available; the choice between them depends on individual clinical factors detailed in the full protocol.

The complete structured regimen — including all available agents, how to select between them, and the full clinical algorithm — is in the protocol below.