Treatment of Primary Hyperparathyroidism in Pregnancy
Primary hyperparathyroidism (PHPT) co-occurring with an active pregnancy is a rare clinical situation that demands a management strategy distinct from the standard non-pregnant approach.
Clinical scenario — PHPT in pregnancy: PHPT in pregnancy is a rare event, and the actual incidence is not fully established. The concurrent presence of PHPT and pregnancy introduces specific considerations around intervention, timing, and fetal safety that shape every management decision.
Approach
In selected pregnant patients, a surgical intervention may be considered — with specific criteria determining candidacy and particular timing windows within the pregnancy being clinically decisive.
Complete eligibility criteria, optimal timing, preoperative workup, and procedural details are in the full protocol →
References
DOI: 10.1002/jbmr.4677
PHPT in pregnancy is a rare event, but the actual incidence of PHPT in pregnancy is not known.
Consider surgery in the second trimester for patients with serum calcium >11.0 mg/dL and for whom surgery is not contraindicated
The opportune timing of PTX under general anesthesia is during the first half of the second trimester.
Preoperative imaging should be limited to ultrasound
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