Postmenopausal vaginal bleeding in the context of endometrial hyperplasia with atypia carries a significant long-term risk. When surgery is not an option for the patient, management requires a structured, multidisciplinary approach.
Patients who are not suitable for surgery should be managed via a multidisciplinary team (MDT) to ensure safe, individualised care.
Where surgical intervention is not possible, management is directed by an MDT. A progestogen-based treatment is central to this approach — a specific local delivery method is preferred over oral preparations. The complete protocol specifies the preferred option and the full clinical pathway.