Treatment of Posterior Uveitis with Confirmed Tuberculous Etiology
When posterior uveitis is caused by tuberculosis and the diagnosis has been microbiologically or clinically confirmed, management follows a distinct, infection-directed pathway that differs substantially from other forms of uveitis.
Clinical Scenario
This protocol applies to patients presenting with tubercular posterior uveitis in whom a tuberculous etiology has been confirmed. Once confirmation is established, prompt initiation of targeted therapy is imperative to prevent ongoing ocular and systemic tissue damage.
Treatment Approach
Management centres on
anti-tuberculous therapy (ATT), which must be initiated under the direct care of an internist. This is combined with a concomitant course of systemic steroids to address inflammatory tissue injury. The full regimen — including agent selection, sequencing, and duration — is detailed in the structured protocol.
Complete regimen, dosing, and stepwise algorithm available via the full protocol.
References
DOI: 10.4103/0301-4738.58470
It is imperative that anti-tuberculous therapy (ATT) be initiated under care of an internist once tuberculous etiology is confirmed.
Concomitant systemic steroids for 4–6 weeks have a protective effect against tissue damage from delayed type of hypersensitivity (DTH).
View source ↗