Treatment of Post COVID-19 Condition with Cough in Long COVID
Persistent cough is a recognised symptom of Post COVID-19 condition (long COVID). Managing it effectively requires evaluation through an established clinical framework and a targeted, evidence-guided approach.
Clinical Scenario
This protocol addresses patients with Post COVID-19 condition who present with cough. Evaluation in this population should be structured around criteria for chronic cough.
Treatment Approach
An empirical antihistamine-based strategy forms the starting point for managing cough in long COVID — the full evidence-based regimen, including additional agents and selection criteria, is detailed in the complete protocol.
References
DOI: 10.3947/ic.2024.0024
For long COVID patients complaining of cough, evaluation should be considered based on criteria for chronic cough (B, IIa).
For the cough symptoms in patients with long COVID, empirically, antihistamines and intranasal corticosteroid use may be considered (G, IIb).
These guidelines recommend H1 antihistamines as the primary empirical treatment for the treatment of nonspecific chronic cough without treatable traits.
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