Portal hypertension
ICD-10 K76.6 · ICD-11 DB98.7

Treatment of Portal Hypertension with Overt Hepatic Encephalopathy in Cirrhosis

Overt hepatic encephalopathy (HE) occurring in a patient with liver cirrhosis is a serious decompensation event requiring structured, prompt intervention. In the context of portal hypertension, this presentation carries significant clinical urgency.

A patient with liver cirrhosis develops overt hepatic encephalopathy — a recognised complication in portal hypertension that demands immediate assessment and targeted management.

The primary clinical objective is improvement in hepatic encephalopathy.

The cornerstone of management is identifying and correcting the precipitant of hepatic encephalopathy. First-line therapy involves non-absorbable disaccharides. The full protocol specifies additional interventions and decision points beyond this initial step.

References

DOI: 10.1016/j.jceh.2022.03.002

Therefore, identifying and correcting the precipitant of HE is the most important aspect in the management of HE.

Non-absorbable disaccharidases are the first-line therapy for overt HE.

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