Polycystic ovarian syndrome
ICD-10 E28.2 · ICD-11 5A80.1

PCOS with Hyperandrogenism and Irregular Periods: First-Line Management

This protocol covers polycystic ovarian syndrome presenting with clinical or biochemical hyperandrogenism and/or irregular menstrual cycles, in patients who have no contraindication to combined oral contraceptive pills.

Clinical Scenario
A patient with PCOS who has clinical or biochemical evidence of hyperandrogenism and/or irregular periods, and no contraindication to a combined oral contraceptive preparation.
Treatment Approach
The recommended first-line intervention involves a combined oral contraceptive pill (COCP). Preparation selection involves specific clinical considerations — including which options should not be considered first line — detailed in full in the structured regimen. Complete preparation guidance and selection criteria available in the full protocol →
Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.fertnstert.2023.07.025
  • The COCP alone should be recommended in adult women with PCOS for management of hyperandrogenism and/or irregular menstrual cycles.
  • The COCP alone should be considered in adolescents with a clear diagnosis of PCOS for management of clinical hyperandrogenism and/or irregular menstrual cycles.
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