Treatment of Active Peyronie's Disease with Penile Pain
This protocol covers management in patients with active Peyronie's disease who are experiencing penile pain — the hallmark symptom of the active disease phase.
The active stage of Peyronie's disease is defined by dynamic, changing symptoms. Penile pain — with or without erection — is the defining clinical feature of this phase, and its severity guides the treatment approach.
Treatment Approach
Pain management in the active phase involves a specific class of oral anti-inflammatory therapy. The complete regimen — including agent selection and management considerations — is detailed in the full protocol.
Clinical goal: Resolution or meaningful improvement of penile pain, tracked with a visual analog scale (VAS) and re-assessed periodically to measure treatment efficacy.
References
- Active disease is characterized by dynamic and changing symptoms.
- Penile and/or glanular pain or discomfort with or without erection is the defining symptom of the active stage.
- Clinicians may offer oral non-steroidal anti-inflammatory medications to the patient suffering from active Peyronie's disease who is in need of pain management.
- Clinicians may offer oral non-steroidal anti-inflammatory agents to help manage pain in the active phase.
- Patient pain level can be assessed using a visual analog scale (VAS).
- Pain level should be periodically re-assessed to measure treatment efficacy.
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