This protocol applies to perioral dermatitis cases in which systemic pharmacological treatment is indicated. The evidence supports a specific systemic agent and approach for this situation.
Systemic antiacne therapy is the basis of this protocol. The full structured regimen — including agent selection, dosing considerations, and sequencing — is available in the complete protocol below.
DOI: 10.1016/j.clindermatol.2013.05.034
If there is no response to the full dose of tetracyclines, the patient may need to be treated with isotretinoin.
Systemic treatment includes antiacne medications such as doxycycline, minocycline, and isotretinoin.
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