Pelvic inflammatory disease (PID) is an infection of the upper female genital tract. Patients with mild to moderate disease are candidates for outpatient empiric management, allowing prompt treatment while avoiding unnecessary hospitalisation.
Outpatient management is built around a single intramuscular injection of a recommended cephalosporin combined with a 14-day oral antibiotic course. Depending on the clinical context, an additional agent targeting anaerobic organisms may be incorporated. For patients in whom the risk of gonorrhoea is assessed as low, an alternative oral-only regimen from a different antibiotic class is available. The full selection criteria, agent options, and sequencing are detailed in the complete protocol.
Clinical improvement is expected within 48 to 72 hours of starting treatment. Follow-up within that window is used to confirm response and assess treatment tolerance.