Lower urinary tract symptoms — particularly increased urinary frequency, urinary urgency, and bladder detrusor overactivity — are recognised autonomic manifestations in patients with Parkinson's disease that require a dedicated management approach.
This protocol applies to patients with Parkinson's disease who present with:
First-line management combines structured non-pharmacological bladder interventions with antimuscarinic therapy — the complete selection criteria, agent choice, and sequencing are detailed in the full protocol.
DOI: 10.1186/s42466-024-00325-4
Non-pharmacological treatment options for neurogenic bladder dysfunction in PD include bladder training, adjusting fluid intake throughout the day, and avoiding caffeine, alcohol, and carbonated drinks.
Antimuscarinics such as Solifenacin, Trospium or Darifenacin can be considered for treatment of increased urinary frequency and urgency due to overactivity of the bladder detrusor in PD patients.