Fatigue is a recognised non-motor symptom of Parkinson’s disease that can significantly affect quality of life and requires specific clinical attention beyond standard motor management.
This protocol addresses Parkinson’s disease patients presenting with fatigue. The presence of fatigue defines a distinct management pathway with targeted therapeutic considerations.
Management in this setting incorporates physical interventions alongside optimisation of dopaminergic medication; further pharmacological options may be considered based on individual patient factors.
Physical interventions are recommended to treat depression, fatigue, and apathy.
For treating fatigue in PD patients, optimal dopaminergic medication should be used, and therapy with Rotigotine may be conducted if individualized Dopamine agonist therapy is possible.
Modafinil or Safinamide may be considered for treating fatigue in PD patients.