This protocol covers the situation in which pathological examination of surgical specimens confirms parathyroid carcinoma following a prior parathyroidectomy. Because the initial operation may not have been performed as a cancer resection, the confirmed diagnosis creates an immediate need for re-evaluation and a defined next step.
Evidence-based guidance in this setting centres on a structured surgical reoperation approach. The specific anatomical scope of that reoperation, along with the critical timing window in which it should occur, is laid out in the full protocol.
DOI: 10.1016/j.esmoop.2024.103664
In case of pathological diagnosis of PC after parathyroidectomy, reoperation with ipsilateral thyroid lobo-isthectomy and central node dissection should be discussed within 1 month of initial surgery [IV, A].
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