What Is the First-Line Treatment of Parathyroid Carcinoma When Diagnosed Preoperatively?

This protocol addresses the first-line management of parathyroid carcinoma (PC) in the setting where a preoperative diagnosis has been established. The recommended approach centres on a defined surgical strategy aimed at avoiding local recurrence.

Surgery is the recommended first-line treatment for parathyroid carcinoma. When PC is confirmed preoperatively, the operative plan includes en bloc resection of the parathyroid lesion along with specified adjacent structures — carried out with particular attention to preserving lesion integrity during removal.

The full scope of the surgical dissection, including which structures are removed and the precise technique, is detailed in the complete structured regimen.