The co-occurrence of acute cholangitis in a patient with acute biliary pancreatitis defines a high-risk clinical picture that demands a specific, time-sensitive management approach distinct from uncomplicated pancreatitis.
The cornerstone of management in this scenario is early endoscopic intervention targeting the biliary source. The critical details — precise timing criteria, procedural thresholds, and the full clinical decision pathway — are contained in the complete structured protocol.
In patients with AP complicated by cholangitis, early ERCP within the first 24 hours has been shown to decrease morbidity and mortality.
DOI: 10.14309/ajg.0000000000002645
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