Paget Disease of Breast
ICD-10 C50.0 · ICD-11 2C6Y

Treatment of Paget Disease of Breast with Palpable Breast Lump and Ductal Carcinoma In Situ

This protocol addresses Paget's disease of the breast presenting alongside a palpable breast lump with confirmed underlying ductal carcinoma in situ (DCIS).

Clinical Scenario

The patient presents with Paget's disease of the breast and an associated palpable mass. Imaging identifies a solitary retroareolar lump, and biopsy confirms low-grade ductal carcinoma in situ (DCIS) of the underlying breast tissue alongside Paget's disease of the nipple-areolar complex.

Treatment Approach (Partial Overview)

Management in this setting involves a surgical approach — the complete treatment algorithm and specific indications are detailed in the full protocol.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.4103/sajc.sajc_107_18

In other scenario there was an associated, solitary lump, size 2.5 cm × 2.0 cm, found on imaging in retroareolar region of the same breast

Core needle biopsy of the lump was s/o low grade DCIS and full thickness biopsy of NAC revealed Pagets' disease

Mastectomy should be reserved for the few occasions, when relapse occurs.

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