What is the Treatment of Ovarian Hyperstimulation Syndrome (OHSS)?

Ovarian hyperstimulation syndrome (OHSS) is a complication of ovarian stimulation that spans a range of severity. The evidence-based approach focuses on outpatient supportive care, with management tailored to the severity of the presentation.

Clinical Goal

Resolution of OHSS — in most women this occurs over a period of 7–10 days with appropriate management.

Treatment Approach

Management is grounded in outpatient supportive care, with guided oral fluid replacement and analgesia as central elements — further interventions are indicated depending on severity.

The complete decision pathway, full list of interventions, and evidence-based regimen are available in the structured protocol below.

Instant Access to Structured Evidence-Based Regimens

References

Fluid replacement is essential to correct hypovolaemia. However, it appears reasonable to encourage women to drink to thirst rather than a set amount.
Paracetamol and oral opiates including codeine can be offered to women for pain relief.
In most women, the condition resolves over a period of 7–10 days.

DOI: 10.1111/1471-0528.70195

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