Ovarian cancer
ICD-10 C56 · ICD-11 2C73

Treatment of Ovarian Cancer in Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT)

Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and aggressive subtype of ovarian malignancy. Its distinct biology requires a specific adjuvant treatment strategy that differs from conventional epithelial ovarian cancer regimens.

This protocol addresses patients with small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) — a rare, high-grade ovarian malignancy recognised as a distinct histological entity.

The recommended approach is adjuvant systemic therapy using intensive multi-agent combination chemotherapy regimens selected for this subtype.

Full regimen options, preferred sequencing, and cycle details are available in the complete structured protocol.

References

  • Small cell carcinoma of the ovary (hypercalcemic type) (SCCOHT)
  • VPCBAE (Vinblastine/Cisplatin/Cyclophosphamide/Bleomycin/Doxorubicin/Etoposide) up to 6 cycles
  • PAVEP (Cisplatin/Doxorubicin/Etoposide/Cyclophosphamide) 4–6 cycles
  • BEP (Bleomycin/Etoposide/Cisplatin) 3–4 cycles
  • Cisplatin/Etoposide 4 cycles
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