Treatment of Ovarian Cancer in Serous Borderline Epithelial Tumor (Low Malignant Potential, LMP)
This protocol addresses the management of ovarian serous borderline epithelial tumor (low malignant potential, LMP) — a primary epithelial lesion with cytologic characteristics suggesting malignancy but without frank invasion — where low-grade serous carcinoma is absent.
Clinical scenario
Ovarian serous borderline epithelial tumor (LMP) without low-grade serous carcinoma. These tumors occupy a distinct category between clearly benign and overtly malignant ovarian epithelial neoplasms, requiring a tailored surgical approach that differs from standard ovarian carcinoma management.
Treatment approach (partial)
Surgery is the primary treatment modality for this tumor type. The specific surgical plan depends on whether a prior resection was complete and on the patient's fertility goals. The full structured protocol details the surgical options, resection criteria, and post-operative management approach — access it below.
References
- Ovarian serous borderline epithelial tumors (low malignant potential [LMP])
- A borderline tumor is a primary epithelial lesion with cytologic characteristics suggesting malignancy but without frank invasion.
- Completion surgery (contralateral USO, hysterectomy) and resection of residual disease
- Fertility-sparing surgery (if fertility desired) and resection of residual disease
- Chemotherapy (IV or IP) has not been shown to be beneficial in ovarian borderline epithelial tumors (LMP).