Treatment of Ovarian Cancer in Malignant Sex Cord-Stromal Tumor of the Ovary
Malignant sex cord-stromal tumors represent a distinct subtype of ovarian cancer with specific management considerations that set them apart from the more common epithelial histologies. Selecting the right approach for this population requires tailored clinical decision-making.
Clinical Scenario
This protocol addresses ovarian cancer arising as a malignant sex cord-stromal tumor — a subtype whose biology and treatment response differ meaningfully from other ovarian malignancies, warranting a dedicated evidence-based pathway.
References
- Malignant sex cord-stromal tumors
- Carboplatin/Paclitaxel
- Docetaxel
- Ifosfamide/Paclitaxel
- Paclitaxel
- Targeted therapy: Bevacizumab (single agent)
- Aromatase inhibitors (eg, Anastrozole, Exemestane, Letrozole)
- Leuprolide acetate or Goserelin acetate (for granulosa cell tumors)
- Tamoxifen