This protocol addresses the management of low-grade serous carcinoma of the ovary — a histologically and biologically distinct subtype of epithelial ovarian cancer with its own treatment considerations.
Low-grade serous carcinoma of the ovary is managed as a specific entity. Adjuvant treatment planning is guided by disease stage at presentation, with approaches varying substantially across stages.
Depending on stage, options include observation or systemic therapy — either chemotherapy or hormone therapy. The selection and sequence of these approaches follow stage-specific criteria detailed in the full protocol.