Grade 1 endometrioid carcinoma of the ovary represents a distinct histologic subtype of ovarian malignancy. Adjuvant treatment decisions in this setting are guided primarily by surgical stage at the time of diagnosis.
This protocol addresses patients with confirmed grade 1 endometrioid carcinoma of the ovary. Because management varies according to stage, the clinical context at presentation determines which adjuvant pathway applies.
Adjuvant management is stage-dependent and may involve observation or systemic therapy — including chemotherapy or hormonal therapy — depending on the extent of disease at diagnosis. The complete stage-by-stage treatment algorithm and the specific options within each pathway are detailed in the full protocol.