Treatment of Platinum-Sensitive Ovarian Cancer at First Recurrence
This protocol addresses ovarian cancer that has recurred following a prior complete remission — specifically, disease that relapses six months or more after completing prior chemotherapy, meeting the clinical definition of platinum-sensitive recurrence.
Clinical scenario
The patient presents with first recurrence of ovarian cancer after a documented complete remission. Relapse occurred at least six months after the end of prior chemotherapy. This platinum-sensitive status is the defining criterion that shapes the treatment approach for this recurrence.
Treatment approach
Combination platinum-based chemotherapy is the preferred strategy for this first platinum-sensitive recurrence — the full protocol specifies the recommended regimen options, the role of additional targeted agents, considerations for secondary surgical intervention, and the criteria for maintenance therapy selection.
References
- Combination platinum-based chemotherapy, preferred for first recurrence (category 1)
- In general, the Panel would recommend combination, platinum-based regimens for platinum-sensitive recurrent disease based on randomized trial data, especially in first relapses.
View source ↗