This protocol addresses otomycosis in the specific situation where clotrimazole-resistant Aspergillus species are clinically suspected or have been isolated from the ear canal — a presentation that requires a different topical approach.
Clinical scenario: Aspergillus species suspected or confirmed in otomycosis, with documented or likely resistance to clotrimazole.
Alternative topical agents to which clotrimazole-resistant Aspergillus species retain susceptibility are available. The complete regimen — including the specific agents, their sequence, and full prescribing details — is in the structured protocol below.
DOI: 10.22541/au.170670973.33825129/v1
If clotrimazole-resistant Aspergillus spp. is suspected or isolated, fluconazole or thiocarbamate eardrops are an option.
These organisms were found to be susceptible to fluconazole and tolnaftate solution.
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