Treatment of Otomycosis with Systemic Antifungal Therapy
Clinical Scenario
This protocol addresses otomycosis in cases where systemic antifungal treatment is indicated — specifically in patients who have not responded to topical antifungal therapy.
Treatment Approach
Systemic antifungal therapy is employed in select otomycosis scenarios; the appropriate agent and route depend on patient-specific factors detailed in the full structured protocol.
References
DOI: 10.22541/au.170670973.33825129/v1
- Systemic antifungals have an important role in specific cases of otomycosis, for example in immunosuppressed patients unresponsive to topical antifungals, in multi-drug resistant Candida auris and Aspergillus infections and in invasive otitis externa.
- In studies where an oral antifungal was prescribed, such as in immunosuppressed patients who were unresponsive to topical antifungals, voriconazole was chosen frequently (36% of studies).
- Amphotericin B was frequently chosen when intravenous treatment was required.
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