Osteomyelitis
ICD-10 M86 · ICD-11 FB84

Treatment of Osteomyelitis in Adults with a Streptococcus-Positive Bone Culture

Clinical Scenario

This protocol applies to adult patients with osteomyelitis whose bone culture has returned positive for Streptococcus species. Antibiotic selection in osteomyelitis is driven directly by culture results; a confirmed Streptococcal isolate defines this specific treatment pathway.

Adult Bone culture: Streptococcus spp.
Treatment Approach

Management is built around targeted antibiotic therapy directed specifically at Streptococcus — a penicillin-class agent is central to this regimen. The complete protocol, including dosing and duration, is available via the link below.

References
  • The choice of antibiotic therapy is specific to the culture results listed in Table 3.
  • Initial Antibiotic Therapy for Osteomyelitis in Adults
  • Streptococcus species
  • Penicillin G, 2 to 4 million units IV every 4 hours
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