In adult patients with osteomyelitis, confirmed bone culture results guide antibiotic selection. When the culture identifies methicillin-sensitive Staphylococcus aureus (MSSA), management is directed specifically by that finding — and the treatment differs meaningfully from empiric or culture-negative approaches.
Adult patient with osteomyelitis; bone culture positive for methicillin-sensitive Staphylococcus aureus. The choice of antibiotic therapy is specific to this confirmed culture result.
This protocol defines targeted intravenous antibiotic therapy for confirmed MSSA osteomyelitis, with more than one recommended agent available. The full regimen — including agent selection, dosing, and schedule — is specified in the complete protocol.