Nonsteroidal anti-inflammatory drugs are the standard conservative starting point for osteoid osteoma. When that approach does not produce the expected radiological and symptomatic response within the anticipated timeframe, an interventional protocol becomes the indicated next step.
Nonsteroidal anti-inflammatory drugs were the first-line approach. This protocol is indicated when that treatment did not achieve radiological healing — specifically, involution of the nidus and progressive sclerosis over the expected 18–24‑month window — or when adequate symptom regression was not reached.
The protocol centres on image-guided percutaneous thermal ablation of the osteoid osteoma nidus, which is currently considered the standard therapeutic strategy for cases refractory to conservative management. The full structured regimen details the technique options and procedural parameters.