Oral lichen planus
ICD-10 L43.8 · ICD-11 EA91.4

Third-Line Treatment Options for Oral Lichen Planus

Oral lichen planus is a chronic inflammatory condition of the oral mucosa that can persist despite initial management. When earlier treatment lines have not achieved adequate control, a structured set of third-line interventions is available.

This protocol covers the third-line management step for oral lichen planus — a broad set of evidence-based options spanning systemic agents, immunomodulatory approaches, light-based therapies, and laser modalities.

Approach at this stage

Third-line intervention draws on a wide range of options — including certain systemic agents, antibiotic and antifungal courses, immunomodulatory compounds, phototherapy regimens, and laser-based procedures. Which agents and sequences apply to a given patient requires the full protocol.

References

DOI: 10.1111/jdv.16464

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