Evidence-Based First-Line Treatment of Oral Candidiasis

References

• As first choice for local treatment has been for years the nystatin at doses of 100 000 IU/ml [5ml 4 times daily] and amphotericin b at 50mg [5ml 3 times per day].
• Fluconazole oral suspension is administered in a dosage of 10 mg / ml aqueous suspension by administering 5 ml daily for 7 or 14 days.
• It has recently been found that fluconazole oral suspension as a local treatment, at a dose of 2 mg/ml 3 times daily or 10 mg /ml once daily, gives good clinical results, besides the better patient compliance due to the dosage and its pleasant taste.
• We found it in the form of gel, applying it directly on the affected area, at doses of 200-500 mg per day, divided into 4 times.
• Moreover miconazole mucoadhesive tablets [50 mg once daily] which are considered effective in the treatment of oropharyngeal candidiasis, but their high cost is one of the main problems.
• Different studies show that it is a very effective drug against pseudomembranous candidiasis, as it has good adhesion to the surface of the oral mucosa and a rapid symptomatic response.