Treatment of Onchocerciasis in Concomitant Lymphatic Filariasis

When onchocerciasis occurs alongside lymphatic filariasis, the co-infection requires a modified management strategy that addresses both parasitic conditions in a coordinated sequence.

Clinical Scenario

This protocol applies to patients with onchocerciasis who have concomitant lymphatic filariasis. The simultaneous presence of both infections means standard single-disease treatment cannot be applied without accounting for the second co-existing condition.

Treatment Approach

Management involves a staged antiparasitic regimen in which the two conditions are treated in a specific, defined sequence rather than simultaneously. The complete protocol — including drug selection, interval, dosing, and full prescribing details — is available below.

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References

In the case of concomitant lymphatic filariasis: administer ivermectin first then start treatment for lymphatic filariasis with doxycycline PO (see Lymphatic filariasis) one week later.

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