Treatment of Ocular Sarcoidosis with Keratoconjunctivitis Sicca (Dry Eye Syndrome) Caused by Lacrimal Gland Granulomas

Clinical Scenario

In ocular sarcoidosis, granulomas involving the lacrimal glands can lead directly to keratoconjunctivitis sicca — a form of dry eye syndrome. This sub-population requires management that specifically addresses the loss of conjunctival moisture arising from lacrimal gland involvement.

Dry Eye Syndrome in This Setting

Lacrimal gland granulomas can lead to keratoconjunctivitis sicca, making maintenance of conjunctival moisture the central clinical concern. The co-occurrence of dry eye syndrome in ocular sarcoidosis shapes both the treatment targets and the choice of interventions.

Management Approach

The protocol focuses on restoring and sustaining ocular surface moisture through topical therapy and supportive ocular measures.

The complete structured regimen — specific agents, procedural options, and their sequencing — is available in the full protocol below.