Non-bullous impetigo
ICD-10 L01 · ICD-11 1B72.1

Treatment of Localised Non-Bullous Impetigo When Not Systemically Unwell

This protocol addresses the management of localised non-bullous impetigo in patients who are not systemically unwell and are not at high risk of complications — a common, uncomplicated presentation.

Clinical scenario Localised non-bullous impetigo; patient not systemically unwell; not at high risk of complications.

Treatment approach

In this scenario, a topical antiseptic cream is the recommended first-line option. The complete structured regimen — including the specific agent, application schedule, and course length — is set out in the full protocol.

Treatment goal Cure or improvement of non-bullous impetigo by the end of the treatment course.
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References

Consider hydrogen peroxide 1% cream for people with localised non-bullous impetigo who are not systemically unwell or at high risk of complications (see recommendations on choice of antimicrobial).

A 5-day course is usually appropriate but can be increased to 7 days based on clinical judgement, depending on the severity and number of lesions.

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