Treatment of Non-bacterial Thrombotic Endocarditis in Antiphospholipid Syndrome with Recurrent Cerebral Embolism

Non-bacterial thrombotic endocarditis (NBTE) in the setting of antiphospholipid syndrome (APS) or another autoimmune disorder is a clinically challenging scenario, particularly when recurrent cerebral embolism has occurred.

Clinical scenario

This protocol addresses patients with antiphospholipid syndrome or another autoimmune disorder who have NBTE complicated by recurrent cerebral embolism. The underlying autoimmune and prothrombotic context is central to weighing management options.

Management approach

Surgical intervention is among the options considered in this setting, with the precise approach determined by each patient's individual clinical presentation. The complete regimen — including how that determination is made — is in the full protocol.

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References

DOI: 10.1016/j.ejcts.2007.07.029

In patients with APS and other autoimmune disorders presenting with recurrent cerebral embolism, the merit of surgical intervention needs to be tailored to the clinical presentation of each patient.

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