What Is the Standard Treatment for Neurosyphilis?

Neurosyphilis is a serious infection of the central nervous system that requires prompt, structured antimicrobial management. First-line treatment relies on high-concentration parenteral antibiotic therapy to achieve adequate CNS drug levels.

Treatment Approach

First-line management involves parenteral antibiotic therapy delivered either intravenously or intramuscularly, sustained over a defined treatment course. Two established routes of administration are supported by guidelines.

Full regimen details — agent selection, dosing, and duration — are in the complete protocol below.
Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1111/jdv.16946

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