What Is the First-Line Treatment for Neurosyphilis?

This protocol covers the evidence-based first-line treatment approach for Neurosyphilis (ICD-10 A52.3 / ICD-11 1A62.0). The complete regimen is available via the link below.

Treatment Approach

First-line management of Neurosyphilis involves high-dose intravenous penicillin therapy. The full protocol specifies the exact agent, dose, frequency, and duration of treatment.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1111/jdv.16946

Benzyl penicillin 18–24 million units IV daily, as 3–4 million units every 4 h for 10–14 days

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