Treatment of Local and/or Regional Recurrence of Sinonasal Carcinoma

Sinonasal carcinoma may recur at the original site or in the regional lymph nodes after initial management. The approach at recurrence depends on whether further surgical intervention is feasible.

Clinical scenario: Local and/or regional recurrence of sinonasal carcinoma — cancer that has returned at or near the primary site, or in regional nodes, following prior treatment.

Treatment approach

Surgery is the primary consideration at recurrence, particularly when it enables subsequent local treatment. When surgery is not feasible, a reirradiation-based strategy using advanced delivery techniques may be an option — the full protocol defines the specific indications and approach.

Instant Access to Structured Evidence-Based Regimens

References

For local and/or regional recurrences, surgery should be considered, especially when post-operative reRT is feasible [IV, A].
ReRT could be considered for local or regional recurrences not amenable to surgery [IV, B].
ReRT with IMRT [IV, A] or IMPT [II, B].

DOI: 10.1016/j.esmoop.2024.104121

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