Treatment of Myoclonic Epilepsy in Infancy with Myoclonic Seizures in Children Younger Than 16

Clinical scenario

This protocol applies to children younger than 16 years of age presenting with myoclonic seizures. Rhythmic myoclonic jerks of the shoulders and arms with tonic abduction — resulting in progressive lifting of the arms during the seizure — are typical features of this presentation.

Treatment approach

Management in this setting involves antiepileptic drug therapy. After initial approaches are evaluated, combination (adjunctive) therapy becomes the relevant strategy in appropriate patients.

The full protocol specifies the indicated agents and the conditions under which combination therapy is applied — details available via the structured regimen below.