What Is the Treatment of Multiple Sclerosis with Recent Relapses or New MRI Lesion Activity?
For people with relapsing multiple sclerosis who are experiencing recent clinical relapses or show evidence of new MRI lesion activity, initiating targeted therapy is supported by clinical evidence.
Clinical scenario
Relapsing form of multiple sclerosis with recent clinical relapses or new lesion activity on MRI — a situation in which active disease management is recommended.
Treatment goals
Reduction of clinical relapses and absence of new MRI lesion activity.
The approach centers on initiating a disease-modifying therapy (DMT) — a category of treatment aimed at reducing relapse frequency and suppressing the formation of new MRI lesions. The full protocol specifies which options are appropriate, how they are selected, and the relevant clinical decision points — available via the link below.
References
DOI: 10.1212/WNL.0000000000005347
- Clinicians should offer DMTs to people with relapsing forms of MS with recent clinical relapses or MRI activity (Level B).
- Clinicians should counsel people with MS that DMTs are prescribed to reduce relapses and new MRI lesion activity.
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