Treatment of Multiple Endocrine Neoplasia Type 2B in Advanced Medullary Thyroid Carcinoma with Diarrhea
Clinical Scenario
This protocol applies to patients with Multiple endocrine neoplasia type 2B who have advanced medullary thyroid carcinoma and present with diarrhea. Diarrhea occurs most frequently in patients with advanced disease and hepatic metastases.
Treatment Approach
Management in this setting involves somatostatin analogs as part of the therapeutic strategy. Local therapies may also be considered — the full sequencing, selection criteria, and regimen details are available in the complete protocol.
References
Diarrhea occurs most frequently in patients with advanced disease and hepatic metastases.
Alternative therapies include somatostatin analogs and local therapies such as surgery or chemoembolization.
DOI: 10.1089/thy.2014.0335
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