Treatment of Multiple Endocrine Neoplasia Type 2A in Cutaneous Metastases of Medullary Thyroid Carcinoma

Clinical Scenario

This protocol addresses patients with Multiple Endocrine Neoplasia Type 2A who develop cutaneous metastases of medullary thyroid carcinoma involving the upper chest, neck, or scalp — a rare complication in this setting.

About This Presentation

Cutaneous metastases are an uncommon manifestation in patients with medullary thyroid carcinoma. When skin lesions appear — particularly across the upper chest, neck, or scalp — the number and distribution of lesions directly inform the choice of local management.

Treatment Approach (Partial Overview)

When cutaneous metastases arise, management may involve surgical intervention where feasible; cases with more extensive lesion burden are addressed through alternative local therapies. The full decision algorithm — including which approach applies to which presentation — is available in the complete protocol.

Specific modalities, sequencing, and supporting evidence are detailed in the structured regimen →

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1089/thy.2014.0335

Patients with MTC rarely develop cutaneous metastases.

If possible cutaneous metastases should be excised surgically.

Multiple cutaneous lesions are best treated by EBRT or ethanol injection.

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