This protocol covers patients with Multiple endocrine neoplasia type 2A whose course is complicated by advanced medullary thyroid carcinoma with diarrhea. Diarrhea is a common occurrence in patients with advanced medullary thyroid carcinoma and markedly elevated calcitonin levels, and its management forms a core part of the clinical picture in this setting.
Alternative therapeutic strategies are available for this scenario, including a class of agents with hormonal pathway activity. The full protocol specifies which options apply and under what conditions — the complete decision algorithm is available via the link below.
DOI: 10.1089/thy.2014.0335
Diarrhea is a common occurrence in patients with advanced MTC and markedly elevated serum Ctn levels.
Alternative therapies include somatostatin analogs and local therapies such as surgery or chemoembolization.
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