Treatment of MEN1 with Bronchopulmonary Neuroendocrine Tumour Showing Growth

This protocol applies to patients with Multiple endocrine neoplasia type 1 (MEN1) in whom a bronchopulmonary neuroendocrine tumour, previously managed with surveillance, has demonstrated growth — a change in behaviour that alters the clinical course of action.

In MEN1, bronchopulmonary neuroendocrine tumours may be followed conservatively under a surveillance programme. When such a tumour shows growth, continued observation alone is no longer the appropriate response. This finding is the key driver for escalation to active intervention.

For locoregional bronchopulmonary neuroendocrine tumours in MEN1 that show growth under surveillance, a surgical approach is recognised as the treatment of choice. The full protocol — including patient selection, the complete management algorithm, and all relevant clinical considerations — is available in the structured regimen below.

Complete protocol details are not shown here; access the full regimen via the link below.