Treatment of Molluscum Contagiosum in Immunocompetent Patients Without HIV
Clinical scenario
Immunocompetent patient with molluscum contagiosum; no HIV infection; no immunosuppression.
About this scenario
This protocol applies to patients who are fully immunocompetent — with no HIV infection and no immunosuppression — presenting with molluscum contagiosum. The intact immune status of this population directly shapes the recommended clinical approach and the expected course of infection.
Treatment approach
In immunocompetent patients without HIV, the evidence-based approach centres on expectant management — the complete protocol specifies what this entails and when it applies.
Full regimen details in the structured protocol →
Treatment goal
Complete resolution of the molluscum infection — typically within 12–18 months, though the timeline may occasionally extend beyond this.
References
DOI: 10.1177/09564624211070705
- Expectant management (no treatment) is recommended for immunocompetent patients (although this recommendation is guided by a Cochrane review of molluscum treatments at non-genital sites).
- We recommend that expectant management is suitable for most immunocompetent patients.
- It will usually take 12–18 months for infection to completely resolve, though occasionally even longer (up to a few years).
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