This protocol addresses molluscum contagiosum presenting with genital lesions in people living with HIV infection or immunosuppression where active treatment is required.
The patient has Human immunodeficiency virus (HIV) infection or is otherwise immunosuppressed and has developed molluscum contagiosum affecting the genital area. The treatment goal is complete clearance and resolution of genital lesions, which also prevents further transmission.
Where active treatment is required, first-line management for genital lesions involves a physical destructive modality. The full protocol specifies which interventions qualify, the criteria for selecting between them, and any considerations specific to this population.
Complete regimen details, decision criteria, and sequencing are available in the structured protocol below.
We suggest that where active treatment is required, similar to immunocompetent individuals, liquid nitrogen and podophyllotoxin remain the first-line treatment options for genital lesions in people living with HIV.
Treatment and full resolution of lesions will prevent further transmission.
DOI: 10.1177/09564624211070705 View source ↗