Treatment of Chronic Severe Primary Mitral Regurgitation
Chronic severe primary mitral regurgitation (PMR) requires structured clinical assessment to determine the appropriate intervention strategy, balancing symptom burden, disease severity, and procedural risk.
This protocol addresses chronic severe primary mitral regurgitation. Indications for intervention depend on symptom status and whether the patient is a candidate for surgical or transcatheter approaches, evaluated with guidance from a multidisciplinary Heart Team.
Treatment approach
In symptomatic patients who are anatomically suitable but carry elevated surgical risk, a transcatheter procedure may be considered — the full protocol defines the precise eligibility criteria, decision algorithm, and the complete evidence-based pathway.
References
DOI: 10.1093/eurheartj/ehaf194
- Indications for surgery in patients with chronic asymptomatic and symptomatic PMR are summarized in Recommendation Table 6 and Figure 11.
- High-risk and elderly patients with chronic PMR, though uncommon, may benefit from a less-invasive M-TEER procedure.
- TEER should be considered in symptomatic patients with severe PMR who are anatomically suitable and at high surgical risk according to the Heart Team.
View source ↗