This protocol applies to patients with metabolic acidosis occurring in the setting of methanol or ethylene glycol poisoning — a presentation where specific clinical findings determine the management approach.
In methanol or ethylene glycol poisoning, the clinical picture may include a markedly elevated anion gap, renal insufficiency, or visual impairment. Each of these findings carries distinct implications for how the protocol proceeds.
The protocol involves renal replacement therapy, with initiation guided by defined clinical thresholds and associated findings. The full protocol specifies the exact decision criteria, conditions for escalation, and the complete management sequence.
Full regimen and clinical decision logic available via the link below.DOI: 10.1053/j.ajkd.2019.01.036
In case of methanol or ethylene glycol poisoning, the experts suggest initiation of renal replacement therapy if the anion gap is above 20 mEq/L or if there is renal insufficiency or visual impairment (EXPERT OPINION).
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