Malignant neoplasm of commissure of lip
ICD-10 C00.6ICD-11 2B6B.0.1
Clinical scenario

Treatment of Malignant Neoplasm of Commissure of Lip with Superficial Field Change Lesion (Leukoplakia or Actinic Keratosis)

This protocol addresses malignant neoplasm of the commissure of the lip arising in the specific context of a superficial field change lesion affecting the external vermilion — either leukoplakia or actinic keratosis.

Specific situation

The defining feature of this sub-population is the presence of a superficial field change lesion of the external vermilion of the lip. Both leukoplakia and actinic keratosis represent premalignant mucosal changes that, when present across the vermilion, substantially influence the surgical management approach.

Treatment approach
Management in this setting involves a surgical approach directed at the external vermilion of the lip. The complete procedural details, clinical decision criteria, and management algorithm are available in the full protocol below.
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References

DOI: 10.1017/S0022215116000499

Superficial field change lesions affecting the external vermilion of the lip such as leukoplakia or actinic keratosis are best managed via a lip shave and mucosal advancement.

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