This protocol applies to patients with intestinal failure due to short bowel syndrome who remain dependent on parenteral fluids or nutrients following the period of intestinal adaptation — a high-dependency population where standard measures have not restored adequate autonomous absorption.
In very severe and refractory cases, a surgical approach involving intestinal transplantation is among the options addressed in the structured regimen. The full protocol details the criteria, pathway, and the specific interventions involved.
The use of glucagon-like peptide 2 (GLP-2) analogues (e.g., teduglutide) is recommended for patients with intestinal failure due to short bowel syndrome who require parenteral fluids or nutrients after the period of intestinal adaptation, in order to reduce or withdraw parenteral support and improve quality of life.
Finally, small bowel or multi-visceral transplantation have also been performed in few, very severe and refractory cases of SBS and IF.
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