Cutaneous or lymphocutaneous sporotrichosis presenting in a patient who is pregnant or breastfeeding — a setting where many standard pharmacologic regimens carry meaningful safety concerns for mother and child.
Pregnancy and breastfeeding limit the use of systemic antifungal agents that would otherwise be employed. Patients who cannot safely receive standard regimens need an alternative strategy that avoids systemic exposure while still addressing the cutaneous lesions.
First-line management in this population centres on a physical, non-pharmacologic intervention applied locally to the affected lesion — rather than systemic drug therapy. The full structured protocol specifies the method, application guidance, and clinical criteria for use.
Complete regimen, parameters, and clinical decision guidance are available in the structured protocol below.
DOI: 10.1086/522765
Local hyperthermia can be used for treating patients, such as pregnant and nursing women, who have fixed cutaneous sporotrichosis and who cannot safely take any of the previous regimens (B-III).
Local hyperthermia can be used for the treatment of cutaneous sporotrichosis in pregnant women (B-III).
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